Abstract #2478

Accelerating High-Resolution Semi-LASER 1H-MRSI Using SPICE

Yibo Zhao^1,2, Yudu Li^1,2, Rong Guo^1,2, Bryan Clifford^1,2, Xin Yu³, and Zhi-Pei Liang^1,2

¹Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, United States, ²Department of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, IL, United States, ³Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States

Most of the current ¹H-MRSI techniques have several major practical limitations, including long data acquisition time, low spatial resolution and poor SNR. To overcome these limitations, we accelerate the semi-LASER technique by incorporating subspace modeling. With this improvement, semi-LASER is cable of achieving 1.9×1.6 mm² resolution in a 1.5 minutes scan, which is a significant improvement over the conventional semi-LASER. This imaging capability has been validated with in vivo experiments, and it may significantly enhance the practical utility of ¹H-MRSI.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.