Meeting Banner
Abstract #2513

Whole-brain 23Na multi-parametric mapping at 7 Tesla

Lisa Leroi1, Jacques Stout1, Arthur Coste1, Ludovic de Rochefort2, Mathieu D. Santin3, Romain Valabrègue3, Franck Mauconduit4, Cécile Rabrait-Lerman1, Fawzi Boumezbeur1, and Alexandre Vignaud1

1CEA - Neurospin, Paris, France, 2CRMBM, UMR 7339, Aix-Marseille University, Paris, France, 3CENIR, ICM, Hôpital Pitié-Salpêtrière, Paris, France, Paris, France, 4Siemens Healthineers, Saint-Denis, France

Quantifying physical properties of sodium could be of benefit to assess more specifically changes in cellular homeostasis accompanying neuroinflammatory or neurodegenerative processes. Here, we performed whole-brain Quantitative Imaging using Configuration States (QuICS) in vivo at 7 Tesla to assess simultaneously Total Sodium Concentration (TSC) and relaxation times (T1 and T2). An acquisition time of 20 minutes was sufficient for a 10 mm3 isotropic resolution. In the future, the use of non-Cartesian trajectories could further reduce the overall acquisition time, opening the way to the additional estimation of the trace apparent diffusion coefficient.

This abstract and the presentation materials are available to members only; a login is required.

Join Here