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Abstract #2515

Measurement of 23Na MRI point-spread function (PSF) using a 3D printing resolution phantom

Paul Polak1,2, Rolf Schulte3, and Michael Noseworthy1,2

1School of Biomedical Engineering, McMaster University, Hamilton, ON, Canada, 2Imaging Research Centre, St. Joseph's Healthcare, Hamilton, ON, Canada, 3GE Global Research, Munich, Germany

Acquisition of in vivo 23Na MRI suffers from many inherent technical challenges, including low signal, short T2 relaxation times, and the necessity of dedicated hardware for transmitting and receiving. Despite these issues, research remains attractive because of sodium’s essential role in cellular homeostasis, pH regulation and action potentials in neurons. Quantification of data acquisition and reconstruction techniques are essential in order to overcome 23Na MRI’s difficulties, and we present measurement of the point-spread functions of 3D radial pulse sequences in resolution phantoms with differing sodium concentrations.

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