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Abstract #2522

Quantitative susceptibility mapping and sodium imaging based analysis of susceptibility and sodium concentrations in the basal ganglia

Till M. Schneider1, Nicolas Behl2, Martin Bendszus1, and Sina Straub2

1Department of Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany, 2Division of Medical Physics, German Cancer Research Center (DKFZ), Heidelberg, Germany

23Na concentrations and iron deposition in cerebral gray matter have both shown to be increased in degenerative and inflammatory cerebral diseases. This study employs sodium imaging and quantitative susceptibility mapping to assess differences in sodium concentrations and susceptibility within the basal ganglia in healthy volunteers at 7T. Results indicate a fundamentally different distribution of 23Na concentrations compared to the distribution of susceptibility within the nuclei of the basal ganglia and suggest that not only susceptibility but also 23Na concentrations may be physiologically distributed in a characteristic manner.

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