Abstract #2523

Using dynamic sodium imaging to assess furosemide action in the porcine kidney

James T Grist¹, Esben Søvsø Szocska Hansen², Rasmus Stilling Tougaard², Frank Riemer³, Christoffer Laustsen⁴, and Ferdia A. Gallagher⁵

¹University of Birmingham, Birmingham, United Kingdom, ²Aarhus Unviersity, Aarhus, Denmark, ³Unviersity of Cambridge, Cambridge, United Kingdom, ⁴University of Aarhus, Aarhus, Denmark, ⁵University of Cambridge, Cambridge, United Kingdom

The ability to image sodium is believed to be a powerful tool to understand physiological processes, however have yet to be effectivity translated to clinical realistic usage. Through the use of an efficient k-space trajectory (3D cones) we have undertaken dynamic imaging of the renal sodium distribution pre and post- a furosemide injection. This work shows a decrease in the cortico-medullary sodium gradient over time, as well as being the first renal study on a clinical system with dynamic sodium imaging.

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