The purpose of this study is to assess possible associations between hepatic histologic features of NAFLD and the T1 and T2 of water and fat, measured by a multi TR, multi TE 1H MRS STEAM sequence that acquires 32 spectra for a range of TRs and TEs in a single breath-hold. In evaluation of 51 adults Water T1 showed a positive association with fibrosis. Water T1 and T2 and Fat T1 and T2 all showed associations with steatosis grade; no other statistically significant associations were observed. This may contribute to noninvasive methods of detection and monitoring of NALFD.
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