Meeting Banner
Abstract #2527

Association of hepatic histologic features with magnetic resonance spectroscopy derived hepatic fat and water T1 and T2 estimates in adults with nonalcoholic fatty liver disease

Alexandra N Schlein1, Claude Sirlin1, Yingzhen Zhang1, Guilherme Cunha1, Rohit Loomba1, and Gavin Hamilton1

1Radiology, University of California, San Diego, San Diego, CA, United States

The purpose of this study is to assess possible associations between hepatic histologic features of NAFLD and the T1 and T2 of water and fat, measured by a multi TR, multi TE 1H MRS STEAM sequence that acquires 32 spectra for a range of TRs and TEs in a single breath-hold. In evaluation of 51 adults Water T1 showed a positive association with fibrosis. Water T1 and T2 and Fat T1 and T2 all showed associations with steatosis grade; no other statistically significant associations were observed. This may contribute to noninvasive methods of detection and monitoring of NALFD.

This abstract and the presentation materials are available to members only; a login is required.

Join Here