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Abstract #2535

Evaluation of the elevated signal at 3.55 ppm in 1H MRS spectra of certain glioma patients

David Hundertmark1, Benjamin Bender1, and Uwe Klose1

1Diagnostic and Interventional Neuroradiology, University Hospital Tuebingen, Germany, Tuebingen, Germany

In MR-spectroscopy of gliomas, sometimes an elevation of the signal at 3.55 ppm at an echo time of 135 ms is found, which can be interpreted as myo-inositol or as glycine. Due to coupling effects, the signal of inositol should be reduced at an echo time of 90 ms, while the glycine signal should be larger than at TE 135 ms. In measurements of glioma patients, which show an enhanced signal at 3.55 ppm at TE 135ms, we found a decreased signal at TE 90. Therefore, we saw no indication of elevated glycine concentration in gliomas.

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