Abstract #2583

Arteriovenous Structure and Blood Flow Abnormalities in Parkinson’s Disease

Chunyan Zhang¹, Bo Wu², Xiao Wang¹, Chen Chen¹, Ruichen Zhao¹, Hong Lu³, Hongcan Zhu³, Bing Xue³, Hong Liang³, Sean Sethi⁴, E. Mark Haacke^2,4, and Jingliang Cheng¹

¹Department of MRI, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, ²Wayne State University, Detroit, MI, United States, ³Department of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, ⁴Magnetic Resonance Innovation INC, Detroit, MI, United States

Few researchers have paid attention to the vascular supply and venous outflow in Parkinson’s disease (PD). In this work, we evaluated arterial inflow and venous outflow and looked for the presence of abnormal venous structure. We found that there was a significant correlation of reduced arterial flow with reduced internal jugular vein (IJV) flow. We also found there were a large number of PD patients with no or little flow in the left IJV compared to healthy control group. These results suggest that abnormal flow could be one factor in the development of or progression of PD in some patients.

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