Abstract #2625

Automated MP2RAGE-based Brain Volumetry for Pediatric Patients: A Clinical Usability Study

Maxence Serru¹, Benedicte Marechal^2,3, Tobias Kober², Leo Ribier⁴, Catherine Sembely Taveau¹, Jean Philippe Cottier⁵, Dominique Sirinelli¹, and Baptiste MOREL¹

¹Pediatric Radiology, CHRU of Tours, Tours, France, ²Advanced Clinical Imaging Technology, Siemens Healthineers, Lausanne, Switzerland, ³Radiology, Lausanne University Hospital, Lausanne, Switzerland, ⁴Pediatric Radiology, CHRU of Tours, Tours, Switzerland, ⁵Neuroradiology, CHRU of Tours, Tours, France

Antenatal and mostly post-natal periods are crucial for brain development, characterized by volume increase, brain maturation, neuronal proliferation, neural migration, and myelination. Head circumference is a reliable clinical assessment of brain volume, correlated with neurodevelopmental outcomes (psychomotor and cognitive development). Particularly in young children, it is a fast and inexpensive tool for brain growth follow-up. Complementarily, brain MRI is becoming more frequently used as a first-line examination for suspected brain development abnormality. In this work, we evaluate the potential of an automated MP2RAGE-based brain volumetry method to objectively support radiologists to better assess brain physiological and pathological cerebral growth.

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