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Abstract #2625

Automated MP2RAGE-based Brain Volumetry for Pediatric Patients: A Clinical Usability Study

Maxence Serru1, Benedicte Marechal2,3, Tobias Kober2, Leo Ribier4, Catherine Sembely Taveau1, Jean Philippe Cottier5, Dominique Sirinelli1, and Baptiste MOREL1

1Pediatric Radiology, CHRU of Tours, Tours, France, 2Advanced Clinical Imaging Technology, Siemens Healthineers, Lausanne, Switzerland, 3Radiology, Lausanne University Hospital, Lausanne, Switzerland, 4Pediatric Radiology, CHRU of Tours, Tours, Switzerland, 5Neuroradiology, CHRU of Tours, Tours, France

Antenatal and mostly post-natal periods are crucial for brain development, characterized by volume increase, brain maturation, neuronal proliferation, neural migration, and myelination. Head circumference is a reliable clinical assessment of brain volume, correlated with neurodevelopmental outcomes (psychomotor and cognitive development). Particularly in young children, it is a fast and inexpensive tool for brain growth follow-up. Complementarily, brain MRI is becoming more frequently used as a first-line examination for suspected brain development abnormality. In this work, we evaluate the potential of an automated MP2RAGE-based brain volumetry method to objectively support radiologists to better assess brain physiological and pathological cerebral growth.

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