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Abstract #2658

Imaging the Cerebral Vasculature Using Ferumoxytol Enhanced Susceptibility Weighted Imaging and Quantitative Susceptibility Mapping at 3T

Yongsheng Chen1,2, Yulin Ge3, Saifeng Liu2, Jiani Hu1,2, and E. Mark Haacke1,2

1Department of Radiology, Wayne State University, Detroit, MI, United States, 2The MRI Institute for Biomedical Research, Bingham Farms, MI, United States, 3Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States

Imaging the major arteries in the brain is straightforward using MR angiography either with or without a contrast agent. However, imaging vessels at the 250μm level is challenging and imaging vessels at the 50μm to 100μm level is essentially impossible even with high field systems. One potential approach to bring them to life is using an iron-based contrast agent to enhance SWI. In this work, we extend the use of Ferumoxytol to image the small cerebral arteries and veins to 3T and show that within a reasonable scanning time, one can obtain superb images of the vasculature of the brain.

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