To compare the image quality of pituitary dynamic contrast-enhanced (DCE) MRI using TWIST and iterative reconstruction TWIST (IT-TWIST). IT-TWIST images were created from the identical rawdata of TWIST. ROI analyses were conducted to evaluate enhancement slope in PS, PL, bilateral cavernous sinus (CS) in enhancement slope map. Four ROIs were applied to temporal SD map as an indicator of temporal noise to evaluate image noise. Enhancement slope of all ROIs but PS was significantly higher in IT-TWIST than that in TWIST. Temporal noise in IT-TWIST was significantly less than that in TWIST in all ROIs.