Meeting Banner
Abstract #2673

Estimating hemodynamic response functions using motor task and resting-state EEG-fMRI data acquired during wakefulness with eyes open

Prokopis C. Prokopiou1, Alba Xifra-Porxas2, Michalis Kassinopoulos2, Marie-Helene Boudrias3, and Georgios D. Mitsis4

1Integrated Program in Neuroscience, McGill University, Montreal, QC, Canada, 2Graduate Program in Bioengineering and Biomedical Engineering, McGill University, Montreal, QC, Canada, 3School of Physical And Occupational Therapy, McGill University, Montreal, QC, Canada, 4Department of Bioengineering, McGill University, Montreal, QC, Canada

In this work, we quantify the fMRI hemodynamic response function (HRF) using task-based (motor) and resting-state EEG-fMRI. We developed a methodology that does not require any assumptions regarding the HRF shape or the relative contribution of different EEG spectral bands to obtain region-specific estimates of the HRF. During the motor task, the EEG β-band was found to have a more pronounced contribution to BOLD variations compared to other bands, and the HRF was mainly negative due to β-band desynchronization and post-movement β-rebound. During resting-state, the contribution of different EEG bands and the HRF estimates varied between subjects, possibly due to low SNR and differences in the subjects’ brain state.

This abstract and the presentation materials are available to members only; a login is required.

Join Here