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Abstract #2738

Quantitative assessment of cerebrovascular structure after carotid revascularization using intraCranial Artery Feature Extraction (iCafe) Technique

Manabu Shirakawa1, Li Chen2, Niranjan Balu1, Wenjin Liu1, Dakota Ortega1, Jinmei Chen1, Theodore Trouard3, Diane Bock4, Wei Zhou4, Chun Yuan1, and Thomas S Hatsukami5

1Radiology, University of Washington, Seattle, WA, United States, 2Electrical Engineering, University of Washington, Seattle, WA, United States, 3Biomedical Engineering, University of Arizona, Tuscon, AZ, United States, 4Surgery, University of Arizona, Tuscon, AZ, United States, 5Surgery, University of Washington, Seattle, WA, United States

The aim is to evaluate the change in intracranial arterial vasculature after carotid revascularization using an intracranial feature extraction (iCafe) technique for quantitative analysis of intracranial arteries from 3D time-of-flight magnetic resonance angiography (TOF MRA). Twenty subjects who received carotid revascularization were enrolled and all patients underwent MRA scans three times: before, within 3 days after, and six months after revascularization. The dataset was processed blindly by 4 reviewers using iCafe. Length and volume of intracranial artery and number of intracranial artery branches increased after surgery. This result suggested increased cerebral blood flow after carotid revascularization.

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