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Abstract #2773

T1-rho in the aging brain: results from large-scale population imaging

Johanna Kramme1, Eberhard D. Pracht1, Gerard Sanroma1, Tony Stöcker1, and Monique M.B. Breteler1,2

1German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany, 2Faculty of Medicine, University of Bonn, Institute for Medical Biometry, Informatics and Epidemiology (IMBIE), Bonn, Germany

Within the Rhineland Study we investigated and report normative brain T1-rho values and their change over age, for a large cohort of 547 participants. Investigated regions were GM, WM, deep gray matter and selected white matter tracts. All investigated regions, except amygdala and accumbens, show a positive trend with age. Total scan time was under six minutes (whole brain), showing the feasibility to provide normative values for a wide range of brain regions in a reasonable amount of time.

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