Abstract #2798

Quantitative analysis of the wall thickness and enhancement ratio of intracranial aneurysms using high-resolution black-blood imaging at 7T

Zihao Zhang^1,2, Qingle Kong^1,3, Xinke Liu⁴, Chengcheng Zhu⁵, Zhaoyang Fan⁶, Jing An⁷, Youxiang Li⁴, and Yan Zhuo^1,2

¹State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, ²The Innovation Center of Excellence on Brain Science, Chinese Academy of Sciences, Beijing, China, ³University of Chinese Academy of Sciences, Beijing, China, ⁴Department of Interventional Neuroradiology, Beijing Neurosurgical Institute and Beijing Tiantan Hospital, Beijing, China, ⁵Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, United States, ⁶Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, ⁷Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China

Three-dimensional turbo-spin-echo (3D-TSE) is increasingly being used in black-blood imaging of intracranial aneurysms. In this study, we optimized the protocol of T1-weighted (T1w) 3D-TSE to reach a high isotropic resolution of 0.40 mm. The inner wall thickness and enhancement ratio were analyzed in sections from ten aneurysms. The segments of aneurysmal walls with a higher wall thickness tend to represent a higher enhancement ratio (Pearson correlation, r = 0.32, p < 0.001). The wall thickness and enhancement ratio should be comprehensively considered to predict the prognosis of intracranial aneurysms.

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