Abstract #2812

Inter-site, inter-subject and inter-session variability of B1+ and B0 in the human brain at 7 tesla.

William T Clarke¹, Olivier Mougin², Ian D Driver³, Catarina Rua⁴, Andrew T Morgan⁵, Susan Francis², Richard Bowtell², Richard Wise³, Adrian Carpenter⁴, Christopher T Rodgers⁴, Keith Muir⁵, and Stuart Clare¹

¹Wellcome Centre for Integrative Neuroimaging, FMRIB, NDCN, University of Oxford, Oxford, United Kingdom, ²Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, United Kingdom, ³Cardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Cardiff, United Kingdom, ⁴Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom, ⁵Imaging Centre of Excellence, University of Glasgow, Glasgow, United Kingdom

At ultra-high field strengths, e.g. 7 tesla, the homogeneity of the transmit B₁⁺-field and the B₀-field decreases compared to lower fields. This can strongly affect the contrast in images especially when imaging large volumes, such as the whole brain.

In this work we measure the mean and variance of B₁⁺- and B₀-fields in whole brain images acquired on four, whole-body human 7T scanners. We demonstrate that inter-subject differences dominate over inter-site differences in explaining the observed B₀- and B₁⁺-field variability. Inter-session differences are not significant.

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