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Abstract #2812

Inter-site, inter-subject and inter-session variability of B1+ and B0 in the human brain at 7 tesla.

William T Clarke1, Olivier Mougin2, Ian D Driver3, Catarina Rua4, Andrew T Morgan5, Susan Francis2, Richard Bowtell2, Richard Wise3, Adrian Carpenter4, Christopher T Rodgers4, Keith Muir5, and Stuart Clare1

1Wellcome Centre for Integrative Neuroimaging, FMRIB, NDCN, University of Oxford, Oxford, United Kingdom, 2Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, United Kingdom, 3Cardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Cardiff, United Kingdom, 4Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom, 5Imaging Centre of Excellence, University of Glasgow, Glasgow, United Kingdom

At ultra-high field strengths, e.g. 7 tesla, the homogeneity of the transmit B1+-field and the B0-field decreases compared to lower fields. This can strongly affect the contrast in images especially when imaging large volumes, such as the whole brain.

In this work we measure the mean and variance of B1+- and B0-fields in whole brain images acquired on four, whole-body human 7T scanners. We demonstrate that inter-subject differences dominate over inter-site differences in explaining the observed B0- and B1+-field variability. Inter-session differences are not significant.

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