Abstract #2818

Improvement of R2* mapping in Alzheimer’s Disease at 9.4T through reduction of B0 fluctuation-induced image artifacts using Navigator Echoes

Elisa Tuzzi^1,2, Gisela Elisabeth Hagberg¹, Alexander Loktyushin ¹, Rolf Pohmann¹, Anja Zeller³, Christoph Laske ⁴, and Klaus Scheffler¹

¹High Magnetic Field, Max Planck Institute for Biological Cybernetics, Tuebingen, Germany, ²Institute for Biomedical Magnetic Resonance, Eberhard Karl’s University, Tübingen and University Hospital Tübingen, Tuebingen, Germany, ³Department of Psychiatry and Psychotherapy, Eberhard Karl’s University, Tübingen and University Hospital Tübingen, Germany, Tuebingen, Germany, ⁴Department of Psychiatry and Psychotherapy, Eberhard Karl’s University, Tübingen and University Hospital Tübingen, Tuebingen, Germany

Ultra-High-Field (UHF) MRI provides a potential non-invasive means to investigate Alzheimer’s Disease (AD). R₂* map is one of the most established MRI techniques to detect iron concentration in the brain. However, image quality can be substantially affected by B0 fluctuation-related-artifacts at UHF. In this study we showed an improvement of the quality of R₂* maps in AD at 9.4T using Navigator Echos approach.

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