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Abstract #2883

Large field-of-view high resolution 3D imaging of the thoracolumbar nerve roots inside the spinal canal

Stefano Mandija1,2, Martijn Froeling1,2, Anja G. van der Kolk1,2, Fredy Visser3, Andreas Rowald4, Loan Nguyen-Mattera5, Roberto Martuzzi5, Jean-Baptiste Ledoux6, Fabio Becce6, Jocelyne Bloch6, Gregoire Courtine4,6, and Cornelis A.T. van den Berg1,2

1University Medical Center Utrecht, Utrecht, Netherlands, 2Utrecht University, Utrecht, Netherlands, 3Philips Healthcare, Best, Netherlands, 4Swiss Federal Institute of Technology, Lausanne, Swaziland, 5Fondation Campus Biotech Geneva, Geneva, Swaziland, 6University Hospital Lausanne, Lausanne, Swaziland

A 3D T2/T1-weighted balanced-SSFP sequence has been developed to visualize the nerve roots inside the thoracolumbar spinal canal and their exit point from the spinal cord for clinical 3T MRI systems and coil setups. This sequence allows acquisition of large field-of-view, high resolution (sub-millimeter), almost isotropic images in less than 5 minutes. Furthermore, it is fully balanced, thus allowing high SNR, and intrinsically flow compensated. Hence, CSF flow artifacts are avoided. The acquired volumes in 15 volunteers showed good contrast between CSF, spinal cord and nerve roots (negative contrast), which could allow adequate visualization of intra-spinal pathologies.

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