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Abstract #2903

MOLLI versus SMART1 mapping for quantitative brain tumor DCE MRI on a 3T GE 750w:  Initial experience

Greg O Cron1,2,3, Michael A Gulak4, Nicholas Majtenyi5, Ian G Cameron1,3,5, and Thanh B Nguyen1,3

1Medical Imaging, The Ottawa Hospital, Ottawa, ON, Canada, 2Ottawa Hospital Research Institute, Ottawa, ON, Canada, 3Radiology, University of Ottawa, Ottawa, ON, Canada, 4Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada, 5Physics, Carleton University, Ottawa, ON, Canada

In radiotherapy of high-grade gliomas, radiation changes (RC) are common. RC and tumor recurrence (TR) may both demonstrate progressive Gd contrast enhancement on follow-up, rendering conventional MRI unhelpful. DCE MRI, however, shows promise for distinguishing RC from TR. We set up a new protocol for brain tumor DCE-MRI on a 3T GE 750w. This protocol involved bookend T1 mapping performed with both MOLLI and SMART1. We found that both T1 mapping sequences gave similar results. Although patient numbers are low at this time, the technique appears promising for distinguishing radiation changes from tumor recurrence.

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