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Abstract #2921

Towards quantitative characterization of brain tumors using synthetic MRI: a preliminary study with pathological confirmation

Hui-ming LIU1, Tie-bao MENG1, Hao-qiang HE1, Liangru Ke1, Long Qian2, Bing Wu2, Guo-ping Yin3, and Chuan-miao XIE1

1Department of Medical Imaging, Sun Yat-sen University Cancer Center, Guangzhou, China, 2GE Healthcare, MR Research China, Beijing, China, 3GE Healthcare, MR Application China, Beijing, China

MRI is widely involved for the diagnosis of brain tumors, and offers qualitative assessment of the tumor with regard to the surrounding brain tissues. However, not only visual inspections may introduce subjective bias, there may be cases that pose challenges for diagnosis even with the use of contrast agent. In this work, a novel relaxation quantification approach named synthetic MRI was applied to 40 patients with glioma or meningioma. Our data showed that both T1 and T2 values of glioma were significant higher than that of meningioma. indicating that synthetic MR may be used for classifying different types of brain tumors.

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