Abstract #2928

Multiple overlapping slab 4D-flow imaging using distributed-spiral acquisition with magnetization transfer (MT) preparation for inflow signal enhancement and simultaneous 3D time-of-flight (3D-TOF) angiogram

Dahan Kim^1,2, Leonardo Rivera-rivera², Patrick Turski³, and Kevin M Johnson^2,3

¹Department of Physics, University of Wisconsin - Madison, Madison, WI, United States, ²Department of Medical Physics, University of Wisconsin - Madison, Madison, WI, United States, ³Department of Radiology, University of Wisconsin - Madison, Madison, WI, United States

Quantification of 4D-flow MRI relies on signal magnitude and phase of blood but can be affected by high signal intensities from surrounding tissues. By acquiring imaging volume in multiple overlapping slabs, together with MT preparation further to saturate tissue, 3D-TOF inflow enhancement can be used to improve vessel signal in the 4D-flow magnitude image. The scan-time penalty associated with acquiring multiple slabs was avoided by accelerating the scan with undersampled distributed-spiral acquisition. The proposed method greatly increased vessel contrast and improved depiction of blood vessels, which for 4D-flow MRI translate to more reliable flow quantification and vessel segmentations.

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