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Abstract #2946

Incidence of enlarged perivascular spaces six-months after aneurysmal subarachnoid hemorrhage: a retrospective MR study

Nivedita Agarwal1,2, Ardalan Zolnourian3, Ian Galea4, Roxana O Carare5, and Diederik Bulters6

1Radiology, Santa Maria del Carmine Hospital, Rovereto, Italy, 2Center for Mind/Sciences, CIMeC, Rovereto, Italy, 3Neurosurgery, University of Southampton, Southampton, United Kingdom, 4Clinical neurosciences, University of Southampton, Southampton, United Kingdom, 5Neuropathology, Faculty of medicine, Southampton, United Kingdom, 6Neurosurgery, University Hospital Southampton, Southampton, United Kingdom

One of the major complications of subarachnoid hemorrhage (SAH) is vasospasm which could last days. This could affect the clearance of interstitial fluid (ISF) from the brain parenchyma by restricting its movement along the intramural periarterial drainage (IPAD) pathway. This would result in dilated perivascular spaces (PVS) which have been shown to be an MR biomarker of failure of IPAD. We explore the hypothesis that patients with hemorrhage will present with an increased prevalence of PVS at six months.

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