We previously performed 31P MRS of the human parotid gland,
but no such study of the submandibular gland has yet been reported. The present work was
designed to evaluate the potential of 31P MRS, using 3D CSI, to simultaneously
measure the phosphorus metabolites of human submandibular and parotid glands. Three
healthy volunteers were examined before and after oral intake of vitamin C. Corresponding
spectra revealed intense adenosine triphosphate (ATP) and phosphocreatine peaks.
Following vitamin C intake, β-ATP decreased in both glands. This preliminary finding indicates that 31P
MRS could provide unique information on the bioenergetics of submandibular and