Abstract #2947

Preliminary Results of 31P Magnetic Resonance Spectroscopy for Human Submandibular and Parotid Glands

Toshiyuki Sato¹, Hiroyoshi Isoda¹, Shigeki Arizono¹, Akihiro Furuta¹, Hironori Shimizu¹, Seiya Kawahara¹, Rinpei Imamine¹, Tsuyoshi Ohno¹, and Kaori Togashi¹

¹Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan

We previously performed ³¹P MRS of the human parotid gland, but no such study of the submandibular gland has yet been reported. The present work was designed to evaluate the potential of ³¹P MRS, using 3D CSI, to simultaneously measure the phosphorus metabolites of human submandibular and parotid glands. Three healthy volunteers were examined before and after oral intake of vitamin C. Corresponding spectra revealed intense adenosine triphosphate (ATP) and phosphocreatine peaks. Following vitamin C intake, β-ATP decreased in both glands. This preliminary finding indicates that ³¹P MRS could provide unique information on the bioenergetics of submandibular and parotid glands.

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