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Abstract #2967

Cine imaging using water (saline) bolus for investigating swallowing problems (dysphagia) in Parkinson’s Disease

Sunita Gudwani1, Prabhakar Upadhyay2, Kamlesh Sharma3, Rajesh Sagar4, Rajinder K Dhamija5, and S. Senthil Kumaran1

1Department of NMR and MRI Facility, All India Institute of Medical Sciences, New Delhi, India, 2Department ENT, Lady Harding Medical College, New Delhi, India, 3Department Physiology, ESI Dental College, New Delhi, India, 4Department of Psychiatry, All India Institute of Medical Sciences, New Delhi, India, 5Department of Neurology, Lady Harding Medical College, New Delhi, India

Swallowing a basic oromotor function for survival, investigated with videofluoroscopy (VFS) and flexible endoscopic evaluation (FEES) have limitations either of ionizing radiation, soft-tissue details or of invasiveness. Further clinical examination is challenged with cognitive impairment in degenerative diseases, so non-invasive technique is required for appropriate management. Cine magnetic resonance imaging (dynamic MRI, dMRI) and T2 weighting visualize saline water hyperintensity signal for tissue-bolus contrast without any gadolinium agent. This pilot study reveals dMRI as sensitive non-invasive technique for measuring all the four phases. In motor degenerative diseases like Parkinson’s Disease aids detecting early signs of dysphagia for optimal intervention.

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