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Abstract #2968

Inefficient cranial venous outflow in patients with Meniere’s disease

Nivedita Agarwal1,2, Christian Contarino3, Giuseppenicolò Frau4, and Eleuterio Toro5

1Radiology, Santa Maria del Carmine, Rovereto, Italy, 2Center for Mind/Brain Sciences, University of Trento, Rovereto, Italy, 3Computational Life Inc., Delaware, DE, United States, 4Otorhinolaryngology, Dr, Rovereto, Italy, 5DICAM, Laboratory of Applied Mathematics, University of Trento, Trento, Italy

Meniere’s disease (MD) patients have a high incidence of abnormal neck venous vessels. This results in hampered cerebral venous outflow, disturbed intracranial dynamics, hampered CFS reabsorption, increased venous pressure and intracranial pressure (ICP), disturbed inner ear circulation and possibly disturbed perilymphatic and endolymphatics fluid spaces. Such disturbed intracranial dynamics may help explain endolymphatic hydrops and underlying mechanisms in MD. In this study we performed magnetic resonance venography (MRV) and phase contrast MRI (PC-MRI) in patients with MD to study the anatomy of the extracranial venous vessels and flow in various cranial compartments.

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