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Abstract #2969

Automatic Brain Tissue Detection using Rapid 3D Quantification of R1 and R2 Rates and Proton Density

Marcel Warntjes1,2, Ida Blystad1,3, Peter Lundberg1,4, and Anders Tisell1,4

1CMIV, Linköping, Sweden, 2SyntheticMR AB, Linköping, Sweden, 3Department of Medical and Health Sciences, Radiology, Linköping, Sweden, 4Radiation Physics, Linköping, Sweden

Absolute quantification of R1 and R2 relaxation rates and proton density PD has been gaining considerable attention in recent years. Quantification provides an absolute scaling of patient properties that is independent of MR scanner settings or imperfections. Simultaneous quantification of R1, R2 and PD has mostly been restricted to 2D acquisitions methods, with relatively thick slices. A novel rapid 3D quantification method provides the maps at 1.2 mm isotropic resolution in 6 minutes scan time. The method was validated against a more established 2D method to measure white matter, grey matter, CSF and myelin volumes in the brain

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