Absolute quantification of R1 and R2 relaxation rates and proton density PD has been gaining considerable attention in recent years. Quantification provides an absolute scaling of patient properties that is independent of MR scanner settings or imperfections. Simultaneous quantification of R1, R2 and PD has mostly been restricted to 2D acquisitions methods, with relatively thick slices. A novel rapid 3D quantification method provides the maps at 1.2 mm isotropic resolution in 6 minutes scan time. The method was validated against a more established 2D method to measure white matter, grey matter, CSF and myelin volumes in the brain
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