Meeting Banner
Abstract #3017

Effects of Tract Length in White Matter Alterations After Sports-Related Concussion: A Diffusion MRI Study from the NCAA-DoD CARE Consortium

Yu-Chien Wu1, Sourajit M Mustafi1, Jaroslaw Harezlak2, Nahla M Elsaid1, Larry M Riggen3, Kevin Koch4, Andrew Nencka4, Timothy Meier4, Yang Wang4, Christopher Giza5, John DiFiori5, Kevin Guskiewicz6, Jason Mihalik6, Stephen LaConte7, Stefan Duma7, Steven Broglio8, Michael McCrea4, Andrew Saykin1, and Thomas McAllister9

1Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, United States, 2Indiana University School of Public Health, Bloomington, IN, United States, 3Biostatistics, Indiana University School of Medicine, Indianapoilis, IN, United States, 4Medical College of Wisconsin, Milwaukee, WI, United States, 5University of California Los Angeles, Los Angeles, CA, United States, 6University of North Carolina, Chapel Hill, NC, United States, 7Virginia Tech University, Roanoke, VA, United States, 8University of Michigan, Ann Arbor, MI, United States, 9Psychiatry, Indiana University School of Medicine, Indianapolis, IN, United States

In the present study, we performed streamline tractography to characterize effects of tract length on white-matter microstructural alterations after sports-related concussion. Streamline length and counts were studied in affected white-matter fiber tracts that were found to have impaired white-matter integrity at some points along the tracts using voxel-based analyses. The results suggested that long fibers in the brains of collegiate athletes who sustained sports-related concussion are more vulnerable to this mild traumatic brain injury.

This abstract and the presentation materials are available to members only; a login is required.

Join Here