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Abstract #3023

MRI quantitative assessment of neonatal hyperbilirubin brain damage

Meng Xiaoli1, Wei Xiaocheng2, Zhang Lei3, Ren Zhuanqin4, and Yang Ruwu5

1Department of Radiology, XIAN XD GROUP HOSPITAL, XIAN, China, 2GE Healthcare China, beijing, China, 3Baoji Municipal Central Hospital, baoji, China, 4Baoji Municipal Central Hospital, Baoji, China, 5XIAN XD GROUP HOSPITAL, XIAN, China

Neonatal hyperbilirubinemia (NHB) is a common clinical disease and can cause bilirubin encephalopathy in severe cases´╝îwhich may lead to serious sequelae such as hearing impairment, visual abnormality and mental retardation in children. Quantitatively evaluating the degree of brain damage in neonates with hyperbilirubinemia is of great significance for the prognosis of neonates.In this study, T1 value was measured in different brain regions of newborns with different serum bilirubin levels using T1 mapping, a new magnetic resonance imaging technology of 3.0T.The threshold value of T1 in neonates with bilirubin brain injury was obtained.It provides the quantitative reference index of neonatal hyperbilirubin brain damage for clinic.

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