Brain atrophy is an established biomarker for dementia. Here we tested the hypothesis that spinal cord atrophy is also an important in vivo imaging biomarker for neurodegeneration associated with dementia. 3DT1 images of Alzheimer Disease, Vascular Dementia and healthy subjects were processed to calculate spinal cord morphological parameters, such as vertebral spinal cord cross sectional areas and volumes. We confirmed the presence of significant spinal cord atrophy in dementia compared to healthy subjects. In particular, the C2-C3 vertebrae area resulted to have a considerable weight both for discriminating and classifying Alzheimer Disease from Vascular Dementia and Healthy control subjects.