This study establishes a correlation between cerebral
perfusion and gas uptake using 1H arterial spin labeling and T2
weighted imaging for cerebral blood perfusion, and inhaled hyperpolarized 129Xe
brain MR imaging for cerebral uptake of a free-diffusible noble gas. Using arterial
transit time and cerebral blood volume maps, along with xenon images, correlation
coefficients between 0.34 and 0.63 was observed for healthy subjects between
the ages 26 and 36 years. The distinct properties of water and noble gas opens
up the opportunity to use them in conjunction to understand aspects of brain
physiology.
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