Abstract #3133

Surfaces Area and Cortical Volume Development of Infant Transverse Temporal Cortex Influenced by Preterm Birth

Xianjun Li¹, Jing Xia², Jian Chen², Li Wang², Miaomiao Wang¹, Congcong Liu¹, Mengxuan Li¹, Xiaocheng Wei³, Gang Li², Dinggang Shen², and Jian Yang¹

¹Department of Radiology, the First Affiliated Hospital, Xi’an Jiaotong University, Xi'an, China, ²Department of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States, ³MR Research China, GE Healthcare, Beijing, China

Development of transverse temporal cortex is essential for speech perception in infants. However, the early morphological development of this cortex has not been fully understood. Additionally, influences of preterm birth on cortical development remain to be investigated. This study assessed cortical development of transverse temporal cortex in preterm and term infants based on surface reconstruction. We found that surface area and cortical volume of transverse temporal cortex underwent rapid changes. Term infants held higher surface area, cortical volume, and asymmetry than preterm infants. These results suggest that preterm birth influences the asymmetry and developmental trajectory of transverse temporal cortex.

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