The mammillary bodies play an important role in episodic memory and spatial memory. However, few studies have focused on their properties in humans due to the limitations of the imaging techniques, their location and small size. In this study, we evaluate brain iron content and volume of the mammillary bodies in subjects with mild cognitive impairment (MCI), Alzheimer’s Disease and healthy individuals using quantitative susceptibility mapping and 3D T1-weighted imaging. There was a slight reduction in volume and increase in susceptibility with age and there were no differences of either susceptibility or volume among the three groups.
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