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Abstract #3179

Functional Impact of Theta Burst Stimulation on Motor Cortex

Marc D Lindley1, Mark Sundman2, Koeun Lim2, Jack-Morgan Mizell2, Viet Ton That2, William Mennie2, Chidi Ugonna1, Nan-kuei Chen1, and Ying-hui Chou2

1Biomedical Engineering, University of Arizona, Tucson, AZ, United States, 2Psychology, University of Arizona, Tucson, AZ, United States

The effect of transcranial magnetic stimulation using intermittent theta burst stimulation (iTBS) on functional connectivity and cortical excitability was tested in a healthy older adult and individuals with mild cognitive impairment. Individuals underwent an iTBS protocol with single pulse cortical excitability tests and-resting state fMRI(rs-fMRI) being performed before and after. Cortical excitability was tested through a pseudorandomized order of intensities of single pulses. Within functional network RS-fMRI analysis was done of the sensorimotor network. Differences in the response between the two populations was observed in both the functional connectivity changes in the sensorimotor network as well as the cortical excitability.

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