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Abstract #3195

Advanced Experimental setup for awake resting-state fMRI in rabbits

Nicola Bertolino1, Daniele Procissi1, Craig Weiss2, Quinn C Smith2, and John F Disterhoft2

1Radiology, Northwestern University, Chicago, IL, United States, 2Physiology, Northwestern University, Chicago, IL, United States

Awake imaging in pre-clinical research is challenging due to the MRI sensitivity to motion and animal’s natural reactivity to unfamiliar and loud environment. In this work we present an experimental setup for resting-state fMRI of rabbits and preliminary data collected with it. Our setup relies on the natural tolerance of rabbit to restraint and a home-designed animal fixing cradle equipped with a 3-channel receiver coil.

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