Abstract #3251

Comparison of cerebrovascular reactivity among patients with sporadic cerebral small vessel disease

Ming-Kang Li¹, Ting-Yu Chang², Kuo-Lun Huang², Mei-Yu Yeh¹, Tsong-Hai Lee², and Changwei W. Wu¹

¹Graduate Institute of Mind, Brain and Consciousness, Taipei, Taiwan, ²Department of Neurology, Stroke Center, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan

Sporadic cerebral small vessel disease (SVD) affects small vessels in the brain and causes cerebrovascular-event-related disability. We separated patients into two groups (acute ischemic stroke and spontaneous intracranial hemorrhage) and then compared their cerebrovascular reactivity (CVR) with normal control. We found there was significant BOLD amplitude decline between normal and ischemic group, but no difference in the temporal estimates between groups.

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