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Abstract #3250

Pulsed ASL prepared 4-Dimensional Dynamic Intracranial MR Angiography at 7T with Improved B1 and B0 robustness

Jin Jin1, Kai Wang2, Xiaoming Bi1, Danny JJ Wang2, and Lirong Yan2

1Siemens Medical Solutions USA, Inc., Los Angeles, CA, United States, 2Keck school of medicine, University of Southern California, Los Angeles, CA, United States

This work enhances the quality of non-contrast enhanced time-resolved 4-dimensional MR angiography (4D-MRA) at 7T, by combining segmented multi-phase acquisition of the FAIR scheme with labeling pulses of improved robustness to B1/B0 inhomogeneity and chemical shift. The gradient-modulated offset independent inversion pulses were optimized for 7T application maximizing MR system performance, while providing uniform inversion, sharp transition and tolerance to chemical shift. 4D-MRA images with higher spatial-temporal resolution were reliably acquired within SAR limit of normal operation mode within 5 minutes, presenting a valuable tool for assessing intracranial vasculature and hemodynamics.

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