Abstract #3273

Altered Connectivity Using Resting State fMRI in SCA1 and SCA2 Patients

Dibashree Tamuli¹, Shefali Chaudhary², S. Senthil Kumaran², Ashok Kumar Jaryal¹, Achal Kumar Srivastava³, and Kishore Kumar Deepak¹

¹Physiology, All India Institute of Medical Sciences, New Delhi, New Delhi, India, ²NMR, All India Institute of Medical Sciences, New Delhi, New Delhi, India, ³Neurology, All India Institute of Medical Sciences, New Delhi, New Delhi, India

Neurodegeneration in cortical and subcortical brain areas are found in SCA type 1 and 2 patients. The structural brain volumetric analysis has been done to know the differential loss of volume of brain areas in SCA type 1 and 2. Especially, to find the functional connectivity of the whole brain in the same SCA patients, we have assessed default mode network using resting state fMRI.

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