We introduce TractEM, a tractography-based whole-brain labeling protocol informed by the Eve Labeling [1] procedures from the single-subject Johns Hopkins white matter atlas [1, 2]. This project proposes to create a resource of manually labelled white matter atlases that is driven by state-of-the-art diffusion tractography, and can be manually created in less than 6 hours. We defined and tested the TractEM protocol on 61 tracts for 20 subjects, with multiple raters per subject, and show moderate to high reproducibility for most labels. TractEM should be a useful resource for generating target templates for automated labeling methods.
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