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Abstract #3390

Compensation of signal loss induced by scanner table vibrations in high b-value DW-TSE for measuring lipids ADC

Dominik Weidlich1, Stefan Ruschke1, MingMing Wu1, Andreas Hock2, Rainer Burgkart3, and Dimitrios C. Karampinos1

1Department of Diagnostic and Interventional Radiology, Technical University Munich, Munich, Germany, 2Health Systems Philips Schweiz, Zurich, Switzerland, 3Clinic of Orthopaedic Surgery, Technical University Munich, Munich, Germany

Fat plays a central role in the incidence of metabolic syndrome but current MRI biomarkers cannot answer questions about fat cell microstructure. Diffusion-weighted measurements are capable of revealing information about fat tissue microstructure but the required strong diffusion weighting induces scanner table vibrations that eventually lead to measurement errors and artifacts. The purpose of this work was to mitigate vibration artifacts by placing a vibration compensation gradient before the diffusion preparation. The approach was tested in a water-fat phantom and in-vivo in the lower leg of a healthy volunteer.

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