Abstract #3427

Alterations of brain white matter tracts in children with abnormal intelligence quotient

Yannan Cheng¹, Chao Jin², Xianjun Li², Congcong Liu², Miaomiao Wang², Xiaocheng Wei³, Yuli Zhang², Fan Wu², and Jian Yang²

¹Department of Radiology, the First Affiliated Hospital, Xi’an Jiaotong University, Xi'an, China, Xi’an, China, ²the First Affiliated Hospital, Xi’an Jiaotong University, Xi'an, China, Xi'an, China, ³MR Research China, GE Healthcare, Bei Jing, People's Republic of China, Bei Jing, China

Studies have shown that brain white matter microstructure is of crucial importance for intelligence. Here, we detailed the alterations of brain white matter tracts in children with abnormal intelligence quotient by comparing the difference of brain white matter tract between the two groups and exploring correlations with intelligence scores based on DTI parameters. Significant differences of ILF, IFO and SLF were found in children with abnormal intelligence quotient. And all these tracts were strongly correlated with intelligence quotient, suggesting the underlying structural origins of lower cognitive function.

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