Diffusion-Weighted imaging (DWI) in abdominal MRI is highly valuable for oncological follow-up-investigations. However, intrinsic limitations of the method, including susceptibility to motion artifacts and poor signal in the retroperitoneum, are of special importance regarding its usage in abdominal examinations. This prospective study compared a standard EPI-DWI with an oncologically optimized prototype DWI in 59 patients with regard to the detectability/characterization of suspicious lesions. The study demonstrated that the oncologically optimized prototype DWI sequence with complex averaging, motion correction between averages, rescaling of motion corrupted averages, and background suppression, significantly increased the reader confidence for lesion characterization/detection in oncological abdominal MRI.
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