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Abstract #3446

Prospective evaluation of motion correction and complex averaging in ultra-high-b-value DWI for image quality and lesion conspicuity in oncologic follow-up examinations

Constantin Dreher1, Tristan Anselm Kuder2, Stefan Windhaber1, Franziska K├Ânig1, Daniel Paech1, Anoshirwan Tavakoli1, Regula Gnirs1, Thomas Benkert3, Heinz-Peter Schlemmer1, and Sebastian Bickelhaupt1

1Radiology, German Cancer Research Center, Heidelberg, Germany, 2Medical Physics in Radiology, German Cancer Research Center, Heidelberg, Germany, 3Siemens Healthcare GmbH, Erlangen, Germany

In oncological, abdominal MRI, the value of motion corrected Diffusion-Weighted Imaging (DWI) including complex averaging with high and ultra-high b-values remains to be defined. This is of special importance regarding the balance between normal tissue suppression and suspicious lesion demarcation. This prospective study investigated 41 patients with an oncologically optimized prototype-DWI (with complex averaging, motion correction between averages, rescaling of motion corrupted averages, background suppression). Image quality, tissue differentiation and lesion detection/characterization were significantly increased in high (b900) as compared to ultra-high (b1500) DWI. At the same time, apparent signal-intensity ratio of lesion/normal tissue was not significantly different.

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