Meeting Banner
Abstract #3457

Adapting Diffusion Weighted Arterial Spin Labelling (DWASL) to use a Single Sided Bipolar Diffusion Gradient to Probe Microvascular Signal

Samantha Paterson1, Antoine Vallatos2, and William Holmes3

1Neuroscience & Psychology, University of Glasgow, Glasgow, United Kingdom, 2University of Edinburgh, Edinburgh, United Kingdom, 3University of Glasgow, Glasgow, United Kingdom

Diffusion Weighted Arterial Spin Labelling uses a pair of bipolar diffusion gradients surrounding a spin echo pulse to image signal in the intravascular and extravascular compartments. We propose moving these gradients to a single sided gradient, reducing Δ and changing where the change to the extravascualar signal starts. Our results show that the ratio has changed from b = 50 to b = 300 s/mm2 for our new single sided sequence. This can give us more information on the intravascular signal, helping to improve the probing of blood brain barrier permeability.

This abstract and the presentation materials are available to members only; a login is required.

Join Here