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Abstract #3460

Evaluation the staging of liver fibrosis using diffusion kurtosis imaging: a pilot study

Jiawei Hu1, Dongmei Guo1, Yang Dong1, Yan Xu2, Bing Wu3, and Lizhi Xie3

1The Second Hospital of Dalian Medical University, Dalian, China, 2The First People’s Hospital of Dalian Jinzhou, Dalian, China, 3GE Healthcare, China, Beijing, China

To investigate the diagnostic value of the quantitative diffusion kurtosis imaging(DKI)parameters in the staging diagnosis of liver fibrosis in rabbits’ model. Twenty-nine successful rabbit models were scanned by a 3T MR scanner (Discovery MR750W, GE,Healthcare, USA). GE AW4.6 Workstation and statistical software helps to evaluate the correlation between quantitative analysis of DKI and METAVIR staging. It is concluded that DKI related parameters might have important diagnostic value for the staging of liver fibrosis.

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