Meeting Banner
Abstract #3471

Diffusion kurtosis imaging–derived histogram metrics for prediction of KRAS/NRAS/BRAF mutations in rectal adenocarcinoma: Preliminary findings

Yanfen Cui1, Zhizheng Zhuo2, and Xiaotang Yang1

1Shanxi Province Cancer Hospital, Taiyuan, China, 2MR Clinical Sciences, Philips Healthcare Greater China, Beijing, China

It was revealed that DKI metrics with whole-tumor volume histogram analysis, especially the K75th parameter, yielded more preferable AUC and specificity values for predicting KRAS/NRAS/BRAF mutations than ADC and D values, and thus may potentially serve as an optimal imaging biomarker for the prediction of KRAS/NRAS/BRAF mutations for guiding targeted therapy.

This abstract and the presentation materials are available to members only; a login is required.

Join Here