This work aimed for ADC histogram and texture features based strategy to identify poorly differentiated hepatocellular carcinoma (HCC) which may own a high risk of recurrence or metastasis. The results showed that ADC histogram and texture features can discriminate HCC grade. The 95th percentile achieved the best result (AUC: 0.772; sensitivity: 90%; specificity: 72%) on ADC signal intensity map, forming a valuable strategy for clinical practice.
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