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Abstract #3494

Impact of different b-value combinations on Radiomics Features of Apparent Diffusion Coefficient in Cervical Cancer

Zilong Yuan1, Yaoyao He2, Yi Rong3, Hao Chen1, Zhaoxi Zhang1, Jianfeng Qiu2, Lili Zheng1, Stanley Benedict3, and Yulin Liu1

1Department of Radiology, Hubei Cancer Hospital, Wuhan, China, 2Medical engineering and technology center, Taishan Medical University, Taian, China, 3Department of Radiation Oncology, University of California Davis Medical Center, Sacramento, CA, United States

There is potential influence of different b-value combinations on evaluation of ADC-based radiomics features. The aim of this study is to investigate the difference between ADC-based radiomics feature extracted from ADC maps with different b-value combinations in cervical cancer. It was found that variable b-value combinations can play substantially impact on radiomics features extracted from corresponding ADC maps in cervical cancer. Therefore, we should pay more attention to the choice of b-value combinations in retrospective and multi-center studies.

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