Abstract #3494

Impact of different b-value combinations on Radiomics Features of Apparent Diffusion Coefficient in Cervical Cancer

Zilong Yuan¹, Yaoyao He², Yi Rong³, Hao Chen¹, Zhaoxi Zhang¹, Jianfeng Qiu², Lili Zheng¹, Stanley Benedict³, and Yulin Liu¹

¹Department of Radiology, Hubei Cancer Hospital, Wuhan, China, ²Medical engineering and technology center, Taishan Medical University, Taian, China, ³Department of Radiation Oncology, University of California Davis Medical Center, Sacramento, CA, United States

There is potential influence of different b-value combinations on evaluation of ADC-based radiomics features. The aim of this study is to investigate the difference between ADC-based radiomics feature extracted from ADC maps with different b-value combinations in cervical cancer. It was found that variable b-value combinations can play substantially impact on radiomics features extracted from corresponding ADC maps in cervical cancer. Therefore, we should pay more attention to the choice of b-value combinations in retrospective and multi-center studies.

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