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Abstract #3498

Using symmetrized temporal gradient profiles for water diffusion pore imaging on a 14.1 T spectrometer

Dominik Ludwig1,2, Frederik Bernd Laun3, Karel D. Klika4, Peter Bachert1, and Tristan Anselm Kuder1

1Department of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, 2Faculty of Physics and Astronomy, Heidelberg University, Heidelberg, Germany, 3Institute of Radiology, University Hospital Erlangen (FAU), Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany, 4Molecular Structure Analysis, German Cancer Research Center (DKFZ), Heidelberg, Germany

Diffusion pore imaging can be used to retrieve the pore-space function of an arbitrary closed pore. While a few publications involving pore imaging using the long–narrow gradient approach exist [1–3], all of them involve the use of sophisticated acquisition schemes like CPMG or involve an additional readout gradient. In this study, we were able to show that it is indeed possible to acquire the pore space function of capillaries with a diameter of 15 µm using a simple modification of the long–narrow gradient scheme on a 14.1 T NMR spectrometer.

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