Simultaneous multislice (SMS) technique accelerates MRI data acquisition. However, slice separation in reconstruction is imperfect. This results in residual leakage between the simultaneously excited slices. For diffusion MRI, repeated pairing of the same slices in the image series leads to repeated leakage of a consistent diffusion signal from the other slice. Studies of this effect on diffusion MRI is sparse. Here, we tested two different SMS acquisition and image reconstruction techniques and quantified resulting errors on all diffusion kurtosis (DKI) metrics in different ROIs. Large errors were observed with SMS compared to singleband acquisitions for all DTI and DKI metrics
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