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Abstract #3511

A Multi-Echo Stejskal-Tanner EPI Sequence for Rapid Measurements of T2 and Diffusion Tensor Correlations

Richard Buschbeck1, Ezequiel Farrher1, Kuan-Hung Cho2, Ming-Jye Chen2, Seong Dae Yun1, Chang-Hoon Choi1, Li-Wei Kuo2,3, and N. Jon Shah1,4,5,6

1Institute of Neuroscience and Medicine 4, Jülich Research Centre, Jülich, Germany, 2Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Miaoli, Taiwan, 3Institute of Medical Device and Imaging, National Taiwan University College of Medicine, Taipei, Taiwan, 4Department of Neurology, RWTH Aachen University, Aachen, Germany, 5Institute of Neuroscience and Medicine 11, Jülich Research Centre, Jülich, Germany, 6JARA - BRAIN - Translational Medicine, Aachen, Germany

Initial phantom and in vivo results of a multi-echo Stejskal-Tanner EPI sequence are presented demonstrating the feasibility of rapid measurements for diffusion tensor and T2 correlations. The diffusion and T2 maps are artefact-free and are found to be very similar to the ones derived from the conventional individual-echo methods. However, the data tend to display slightly overestimated diffusivities and T2, which need to be investigated further.

Compared to the standard method, the proposed multi-echo sequence reduces the scan time by a factor of five, which is necessary to make multidimensional diffusion techniques feasible in clinical settings.

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